The investment thesis connects the key links in the healthcare value chain: technology transfer, research, manufacturing, clinical infrastructure and specialised logistics.
Technology and localisation
Transfer of capabilities to Kazakhstan and gradual deepening of local production.
Real assets
Manufacturing, medical and logistics infrastructure supported by operating capabilities.
Scaling
Local demand, regional development and long-term competitiveness.
APEX FUND II
Eight Fund II investment projects at different stages of development.
Temperature-controlled logistics infrastructure for storage and regional distribution of sensitive products. 5PL logistics
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APEX Fund II
Khan Tengri Biopharma
Capital raising · Biopharmaceuticals A full-cycle biopharmaceutical complex in the Alatau SEZ with technology transfer and phased deepening of manufacturing localisation. Khan Tengri Biopharma forms the manufacturing foundation of Fund II's pharmaceutical portfolio. The project focuses on producing complex and strategically important medicines, developing biotechnology capabilities and progressively increasing the depth of local manufacturing. Key parameters
Capital raising
58 SKUs
16.5 ha
2026–2028 — design and construction
December 2028 — target production launch
Investment rationale Project value is created through a combination of technology transfer, physical manufacturing infrastructure, the product portfolio and a phased transition to deeper stages of localisation. The technology partner in the current project model is R-Pharm. Role in the investment strategy A flagship biopharmaceutical manufacturing asset and a capability base that can support other pharmaceutical projects in the portfolio. Focus areas Oncology and haematology; orphan and autoimmune diseases; cardiology and metabolic diseases; diagnostics and infectious diseases. Project website ↗
Capital raising · Personalised medicine A compounding pharmacy and personalised medicine platform combining patient-specific preparation, clinical capabilities, bioanalytics, education and quality control. Khan Tengri Compound focuses on preparing medicines for individual patient needs and developing capabilities at the interface between industrial pharmaceutical manufacturing and clinical application. The project model includes patient-specific preparation, personalised and orphan solutions, bioanalytical infrastructure and quality control. Key parameters
Compounding pharmacy
Clinical and educational centres
Bioanalytical research
Quality-control laboratories
Investment rationale Personalised medicine requires smaller batches, closer integration with the clinical environment and advanced analytical infrastructure. The project creates a distinct highly specialised segment within the Fund II portfolio without the need to scale it as mass production. Role in the investment strategy A clinical, analytical and personalised layer of the portfolio complementing major manufacturing assets and research themes.
Structuring · Active pharmaceutical ingredients A regional centre for small-scale GMP production of active pharmaceutical ingredients for finished dosage form manufacturers. API HUB focuses on producing pharmaceutical substances in small and medium batches for finished dosage form manufacturers in Kazakhstan and regional markets. The model combines specialised process equipment, a GMP environment and a product basket with varying production complexity. Key parameters
≈4 tonnes of APIs per year — planned capacity
Oncology APIs
Cardiology / diabetes
Basic pharmaceutical substances
Investment rationale Local API production reduces the dependence of finished dosage forms on imported upstream supply chains and builds capabilities closer to the start of the pharmaceutical value chain. Small-scale production enables work with more complex and specialised products. Role in the investment strategy Upstream manufacturing infrastructure complementing finished-dosage-form and biotechnology projects.
Structuring · R&D and pharmaceuticals Research, development and manufacturing of high-technology medicines and vaccines. Key Pharma builds a research and product platform for the development and subsequent localisation of high-technology medicines. The project focuses on therapeutic areas where product expertise, regulatory strategy and access to technology are as important as manufacturing infrastructure. Key parameters
42 INNs
Oncology
Pulmonology
Vaccines
Metabolic diseases · HIV · immunology
Investment rationale Unlike projects whose value is driven mainly by physical infrastructure, Key Pharma creates value through its product portfolio, R&D, technology partnerships and the transfer of products into local manufacturing and registration pathways. Role in the investment strategy The innovation and product layer of the portfolio, building a pipeline of developments for localisation and manufacturing of complex medicines.
Structuring · Veterinary medicine Localisation of veterinary medicines, vaccines and diagnostics with phased development of the manufacturing base and regional export potential. VET Pharma creates a dedicated life-sciences vertical focused on biological safety in agribusiness. The project model includes localisation of veterinary medicines, vaccines and diagnostics with gradual expansion of the product portfolio. Key parameters
1 — diagnostics and basic biologics
2 — high-volume cattle/small-ruminant vaccines
3 — poultry vaccines and services
4 — regional exports
Investment rationale Livestock farming creates sustained practical demand for prevention, diagnosis and treatment of animal diseases. A local manufacturing base can reduce import dependence, adapt the product portfolio more quickly to regional epizootic conditions and build export potential. Role in the investment strategy A standalone veterinary life-sciences vertical extending the portfolio's healthcare capabilities beyond human medicines.
Structuring · Medical technology Technology transfer and localisation of high-technology diagnostic medical equipment manufacturing. KTC Medical Technology focuses on creating local manufacturing capabilities in complex diagnostic equipment. The project covers equipment used in advanced imaging and diagnostics and requires not only equipment supply but also a sustainable engineering and service framework. Key parameters
MRI
CT
Angiography systems
Mammography
Investment rationale MedTech localisation creates a physical manufacturing asset, technology capabilities and a more resilient lifecycle-support infrastructure for equipment. The current project model envisages technology cooperation with Beijing Wandong Medical Technology. Role in the investment strategy The portfolio's core MedTech asset, complementing pharmaceutical and healthcare infrastructure with diagnostic technologies.
Structuring · Medical infrastructure A healthcare infrastructure project combining perinatal, multidisciplinary inpatient and oncology care. The hospital complex forms a major healthcare infrastructure asset in the Fund II portfolio. The concept brings several clinical disciplines together in one facility and enables shared engineering, diagnostic and service infrastructure. Key parameters
650 beds — planned capacity
150 — perinatal centre
300 — multidisciplinary inpatient hospital
200 — oncology unit
≈4.4 ha
Investment rationale Healthcare infrastructure creates a long-term real asset whose key factors include design, CAPEX discipline, equipment, the clinical model, staffing and sustainable demand for medical services. Role in the investment strategy The downstream clinical layer of the healthcare value chain, extending the portfolio from technology and product manufacturing to their use in medical infrastructure.
Structuring · 5PL logistics Temperature-controlled logistics infrastructure for storage and regional distribution of pharmaceutical products and other sensitive categories. The 5PL complex is conceived as a modern logistics asset for categories where storage quality, traceability and transport-condition management directly affect product integrity. Pharmaceutical logistics is one of the key target segments. Key parameters
Temperature control
Regional distribution
Pharmaceuticals
Household chemicals
Food products
Investment rationale Specialised logistics creates an infrastructure layer between producer and market. The project's potential value comes from serving multiple customer categories, regional distribution and the ability to support Fund II projects without assuming mandatory intra-portfolio supply commitments. Role in the investment strategy The portfolio's logistics and distribution layer, complementing manufacturing and healthcare assets.
Khan Tengri Compound · VET Pharma · KTC Medical Technology
04
Medical infrastructure
Multidisciplinary Hospital
05
Logistics and distribution
Modern 5PL Warehouse Complex These connections show potential synergies and a shared investment architecture. They do not imply contractual obligations between projects.
A growing market with strong localisation needs
Kazakhstan's pharmaceutical market combines value growth, a significant role of public-sector demand and a high share of prescription medicines. For Fund II, this creates a long-term foundation for projects that localise technologies, manufacturing capabilities and critical healthcare infrastructure.
≈ USD 2.5 bn
Size of Kazakhstan's pharmaceutical market
+15%
Year-on-year market growth in tenge
≈43%
Share of the public segment
≈72%
Share of prescription medicines in value sales
Historical market snapshot: IQVIA, Facts from IQVIA — Eurasia, June 2025, slides 3–4 ↗. MAT’6’25 covers July 2024–June 2025; retail and public channels, at trade prices. The 15% increase is in KZT versus the previous MAT period; public-sector and Rx shares are by USD sales value. These are market indicators, not fund performance.
Project and portfolio risk management
Healthcare projects face risks across technology, regulation, construction, the commercial model and the partner chain. Fund II assesses these areas before investing and throughout implementation.
01
Technology and transfer
Technology maturity, scale-up, equipment and critical suppliers.
02
Regulation and quality
GMP, registration, qualification, validation and permits.
03
Budget and schedule
Design, construction, procurement and commissioning-delay risk.
04
Market
Demand, pricing, reimbursement and competition.
05
Partners and governance
Counterparties, capital structure and execution control. Apex Management GP is responsible for investment management. Licences, construction, manufacturing and operations are the responsibility of the respective project companies.
From technology and CAPEX to a managed investment asset
The specific structure depends on the project, but Fund II follows one principle: technology, capital, project execution, commercial model and risk management must be integrated into a single controlled investment structure.
01
Technology and partnership
Product, technology, scope of transfer and localisation requirements.
02
Project and capital
Project company, capital expenditure and financing structure.
03
Market and commercial model
Demand, procurement model and applicable sales arrangements.
04
Execution and control
Schedule, qualification, GMP, registration, budget and KPIs.